課程資訊
課程名稱
 生醫電子電路設計
Bioelectronics Circuit Design 
開課學期
 110-1 
授課對象
 電機資訊學院  電子工程學研究所  
授課教師
 簡俊超 
課號
 EEE5058 
課程識別碼
 943EU0600 
班次
  
學分
 3.0 
全/半年
 半年 
必/選修
 選修 
上課時間
 星期一2,3,4(9:10~12:10) 
上課地點
 電二101 
備註
 本課程以英語授課。
總人數上限：30人 
  
課程簡介影片
 
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課程大綱
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課程概述

This course covers essential topics for electronics in bioinstrumentation, biomedical devices, and biosensors. 

課程目標
 The students will learn (1) the signal transduction mechanisms in different types of biosensors, (2) understand how to define system specifications based on sensor requirements including dynamic range, noise analysis, linearity, power consumption, and (3) design complete signal conditioning circuits with various low-noise and low-power circuit techniques such as current re-use, correlated-double-sampling (CD), and chopping stabilization. Topics include biopotential measurements of ECG and/or neural action potentials, current readout interface circuits for electrochemical and optical sensors, charged-based readout using FET-transistors, magnetic sensors, and emerging topics in powering, wireless communication, microfluidics, electrochemistry, DNA-based sensor, COVID-19 detection, and etc. We will cover gm/Id design methodology for the amplifiers, CMOS chip layout techniques, fundamental of analog-to-digital converters (ADC), successive-approximation register (SAR) ADC, high-resolution oversampling ADC, and various simulation techniques. 
課程要求
 Prerequisite: Basic course on signal and system/fundamental circuit concepts.
The course will be given in English. 
預期每週課後學習時數
  
Office Hours
 每週四 12:00~13:00
每週一 12:10~13:10 備註： Or by appointment 
指定閱讀
 教課書: 自編課程講義 (lecture notes). 
參考書目
 參考書目:
1. Gray, Hurst, Lewis, Meyer, Analysis and Design of Analog Integrated Circuits, 5th Edition, John Wiley & Sons, 2009.
2. B. Razavi, Design of Analog CMOS Integrated Circuits, 1st Edition, McGraw Hill, 2001.
3. Carusone, Johns, Martin, Analog Integrated Circuit Design, 2nd Edition, John Wiley & Sons, 2012.
4. Pavan, Schreier and, Temes, Understanding delta-sigma data converters, 2nd Edition, Wiley, 2017.
5. Various materials to be distributed throughout the course. 
評量方式
(僅供參考)
  
No.
項目
百分比
說明
1. 
 Homework 
25% 
  
2. 
 Midterm 
25% 
  
3. 
 Final 
25% 
  
4. 
 Project 
25% 
  
 
課程進度
週次
日期
單元主題
第2週
 9/27  Course introduction 
第3週
 10/04  Signal conditioning and biopotential physiology 
第4週
 10/11  Holiday 
第5週
 10/18  Amplifier design, feedback review 
第6週
 10/25  Noise analysis and low-noise techniques 
第7週
 11/01  ADC fundamentals and SAR-ADC introduction and design 
第8週
 11/08  Oversampling concepts and Delta-Sigma modulator introduction 
第9週
 11/15  Midterm 
第10週
 11/22  Introduction of affinity biosensor
 
第11週
 11/29  Electrochemistry, current interface circuits, and charge-based readout circuits 
第12週
 12/06  Optical sensing and magnetic sensing 
第13週
 12/13  Oscillator-based sensors 
第14週
 12/20  Microfluidics 
第15週
 12/27  Energy harvesting and power management design 
第16週
 1/03  Wireless communication for bioelectronics 
第17週
 1/10  Final